How MORE THAN SILVER™ disrupts and destroys biofilm
AQUACEL® Dressing
發展出AQUACEL® Ag+ Dressing的技術是經歷許多年研究，ConvaTec廣泛嘗試了各種可能破壞生物膜的製劑與界面活性劑，以及合併使用各式各樣的抗菌成份1。我們找出了25萬種有潛力的配方組合，並從中挑選了6萬種進行層層測試。
結果如何?
MORE THAN SILVER™技術，包含三種成分，具有瓦解並摧毀生物膜的能力。
MORE THAN SILVER™是由什麼所組成
UNITED AGAINST BIOFILM
我們結合了MORE THAN SILVER™與Hydrofiber®，使敷料能吸收傷口滲出液並瓦解生物膜與殺菌。浙有助於維持傷口適當濕潤環境並促進癒合9。
LEARN MORE ABOUT :
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2. Said J, Walker, M, Parsons D, Stapleton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceutics. 2014; 474: 177-181. DOI 10.1016/j ipharm.2014.08.034.
3. Composition comprising antimicrobial metal ions and a quaternary cationic surfactant WO12136968 Parsons World patent application 11th October 2012.
4. Banin E., Brady K.M. & Greenberg E.P. (2006). Chelator Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in Biofilm. Appl. Environ. Microbiol. 72. 2064 2069.
5. Chen X, Stewart PS, 2000. Biofilm removal caused by chemical treatments. Wat. Res.
6. 4229 4233. 34. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, anto microbial dressing on in vivo, Pseudomonas aeruginosa wounds biofilm: quantitative comparative analysis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712-719. DOI: 10.1111/wrr.12232.
7. Hobot JA, Walker M, Newman GN, Bowler PG. 2008. Effect of Hydrofiber® wound dressings on bacterial ultrastructure. J Electr Micro; 57: 67-75.
8. T. J. Beveridge. W. S. Fyfe. Metal fixation by bacterial cell walls. Canadian Journal of Earth Sciences, 1985, 22(12): 1893-1898, https://doi.org/10.1139/e85-204.
9. Parsons, D, Meredith K, Rowlands VJ, Short D, Metcalf DG, Bowler PG. Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing. Biomed Res Int. 2016;2016:7616471.